This book constitutes the refereed proceedings of the 13th International Conference on Text, Speech and Dialogue, TSD 2010, held in Brno, Czech Republic, September 2010. The 71 revised full papers presented together with 3 invited papers were carefully reviewed and selected from 144 submissions. The topics of the conference include, but are not limited to text corpora and tagging, transcription problems in spoken corpora, sense disambiguation, links between text and speech oriented systems, parsing issues, multi-lingual issues, information retrieval and information extraction, text/topic summarization, machine translation, semantic web, speech modeling, speech recognition, search in speech for IR and IE, text-to-speech synthesis, emotions and personality modeling, user modeling, knowledge representation in relation to dialogue systems, assistive technologies based on speech and dialogue, applied systems and software, facial animation, as well as visual speech synthesis.