This book constitutes the thoroughly refereed post-workshop proceedingsof the 22nd International Workshop on Languages and Compilers forParallel Computing, LCPC 2009, held in Newark, DE, USA, in October 2009.The 25 revised full papers and 5 revised short papers presented werecarefully reviewed and selected from 52 submissions. The papers addressall aspects of languages, compiler techniques, run-time environments, and compiler-related performance evaluation for parallel andhigh-performance computing and extend the area of interest to newparallel computing accelerators such as IBM Cell processor and GraphicProcessing Unit (GPU) presenting the latest work of leading researchersand practitioners in the field.