This book constitutes the proceedings of the 15th International Workshop onFormal Methods for Industrial Critical Systems, FMICS 2010 held in Antwerp, Belgium, in September 2010 - co-located with ASE 2010, the 25th IEEE/ACMInternational Conference on Automated Software Engineering, The 14 papers presented were carefully reviewed and selected from 33submissions.The aim of the FMICS workshop series is to provide a forum for researcherswho are interested in the development and application of formal methods inindustry. It also strives to promote research and development for theimprovement of formal methods and tools for industrial applications.