This book constitutes the refereed proceedings of the 9th International Conference on Unconventional Computation, UC 2010, held in Tokyo, Japan, in June 2010.The 15 revised full papers presented together with 4 extended abstracts of invited talks, and 8 abstracts of posters were carefully reviewed and selected from numerous submissions. The papers are devoted to all aspects of unconventional computation --- theory as well as experiments and applications. Typical topics are: natural computing including quantum, cellular, molecular, membrane, neural, and evolutionary computing, as well as chaos and dynamical system-based computing, and various proposals for computational mechanisms that go beyond the Turing model.